I'm having the exact issue as described by the author.
Tried reinstall, repair etc doesn't work at all.
I've also checked the certificate to be SHA256.
Pulse Secure Window Client ver 9.0.3(1667)
at the taskbar, it does write "Pulse secure service is not running" but "pulse secure access service" is indeed running under task manager tab.
Following is the debug.log
00172,09 2019/04/24 00:38:46.289 1 PK Pulse.exe Pulse p8664 t22B0 accessServiceApi.cpp:131 - 'AccessServiceProxy' createInstance of plugin jamUIPlugin failed with error 0xe00103ee 00132,09 2019/04/24 00:38:46.295 3 PK Pulse.exe Pulse p8664 t22B0 DialogManager.cpp:196 - 'JamUI' No plugin interface available - rc = 1006 00230,09 2019/04/24 00:38:46.351 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:117 - 'AccessService' plugin C:\Program Files (x86)\Common Files\Pulse Secure\JamUI\uiModelService.dll, invalid signature 00198,09 2019/04/24 00:38:46.352 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:611 - 'AccessService' trying to create instance on plugin uiModelService while in state 1 00175,09 2019/04/24 00:38:46.352 1 PK Pulse.exe Pulse p8664 t22B0 accessServiceApi.cpp:131 - 'AccessServiceProxy' createInstance of plugin UiModelService failed with error 0xe00103ee 00167,09 2019/04/24 00:38:46.352 3 PK Pulse.exe Pulse p8664 t22B0 JamConnectionModel.cpp:291 - 'JamUI' Connection to UIModelService plugin failed - service may not be running 00224,09 2019/04/24 00:38:47.293 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:117 - 'AccessService' plugin C:\Program Files (x86)\Common Files\Pulse Secure\JamUI\uiPlugin.dll, invalid signature 00195,09 2019/04/24 00:38:47.293 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:611 - 'AccessService' trying to create instance on plugin jamUIPlugin while in state 1 00172,09 2019/04/24 00:38:47.293 1 PK Pulse.exe Pulse p8664 t22B0 accessServiceApi.cpp:131 - 'AccessServiceProxy' createInstance of plugin jamUIPlugin failed with error 0xe00103ee 00132,09 2019/04/24 00:38:47.294 3 PK Pulse.exe Pulse p8664 t22B0 DialogManager.cpp:196 - 'JamUI' No plugin interface available - rc = 1006 00230,09 2019/04/24 00:38:47.347 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:117 - 'AccessService' plugin C:\Program Files (x86)\Common Files\Pulse Secure\JamUI\uiModelService.dll, invalid signature 00198,09 2019/04/24 00:38:47.347 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:611 - 'AccessService' trying to create instance on plugin uiModelService while in state 1 00175,09 2019/04/24 00:38:47.347 1 PK Pulse.exe Pulse p8664 t22B0 accessServiceApi.cpp:131 - 'AccessServiceProxy' createInstance of plugin UiModelService failed with error 0xe00103ee 00167,09 2019/04/24 00:38:47.347 3 PK Pulse.exe Pulse p8664 t22B0 JamConnectionModel.cpp:291 - 'JamUI' Connection to UIModelService plugin failed - service may not be running 00224,09 2019/04/24 00:38:48.286 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:117 - 'AccessService' plugin C:\Program Files (x86)\Common Files\Pulse Secure\JamUI\uiPlugin.dll, invalid signature 00195,09 2019/04/24 00:38:48.286 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:611 - 'AccessService' trying to create instance on plugin jamUIPlugin while in state 1 00172,09 2019/04/24 00:38:48.286 1 PK Pulse.exe Pulse p8664 t22B0 accessServiceApi.cpp:131 - 'AccessServiceProxy' createInstance of plugin jamUIPlugin failed with error 0xe00103ee 00132,09 2019/04/24 00:38:48.287 3 PK Pulse.exe Pulse p8664 t22B0 DialogManager.cpp:196 - 'JamUI' No plugin interface available - rc = 1006 00230,09 2019/04/24 00:38:48.349 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:117 - 'AccessService' plugin C:\Program Files (x86)\Common Files\Pulse Secure\JamUI\uiModelService.dll, invalid signature 00198,09 2019/04/24 00:38:48.349 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:611 - 'AccessService' trying to create instance on plugin uiModelService while in state 1 00175,09 2019/04/24 00:38:48.349 1 PK Pulse.exe Pulse p8664 t22B0 accessServiceApi.cpp:131 - 'AccessServiceProxy' createInstance of plugin UiModelService failed with error 0xe00103ee 00167,09 2019/04/24 00:38:48.350 3 PK Pulse.exe Pulse p8664 t22B0 JamConnectionModel.cpp:291 - 'JamUI' Connection to UIModelService plugin failed - service may not be running 00224,09 2019/04/24 00:38:49.288 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:117 - 'AccessService' plugin C:\Program Files (x86)\Common Files\Pulse Secure\JamUI\uiPlugin.dll, invalid signature 00195,09 2019/04/24 00:38:49.288 1 SYSTEM PulseSecureService.exe dsAccessService p3544 t1080 accessPluginLoader.cpp:611 - 'AccessService' trying to create instance on plugin jamUIPlugin while in state 1 00172,09 2019/04/24 00:38:49.288 1 PK Pulse.exe Pulse p8664 t22B0 accessServiceApi.cpp:131 - 'AccessServiceProxy' createInstance of plugin jamUIPlugin failed with error 0xe00103ee 00132,09 2019/04/24 00:38:49.288 3 PK Pulse.exe Pulse p8664 t22B0 DialogManager.cpp:196 - 'JamUI' No plugin interface available - rc = 1006
This is an old thread from 2016 - you may wish to raise a support case if this is still a problem?
Yes, I just revived this old post due to the fact that i'm facing exactly the same issue.