You can use the jamcommand program to update the connection store, no need to reinstall the Pulse Client for updating the VPN connections.   Run jamCommand with the .pulsepreconfig file as an option/argument. For example:   On Windows: C:\Program Files (x86)\Common Files\Pulse Secure\JamUI\jamCommand -importfile <pulsepreconfig file>   If the Pulse client is running when you run jamCommand, the new Pulse connection or connections appear immediately.   Reference - https://kb.pulsesecure.net/articles/Pulse_Secure_Article/KB44037   NOTE: Make sure the new preconfiguration which you'e using has the updated connection details.   ... View more

Unfortunately, no; IE only downloads the PAC file once and if the content is not available without the VPN tunnel, it will not refresh until a new launch is done You should be ok to "simply" launch a new instance to get the proxy information. You may be able to see a different behavior without the unsupported "automatically detect settings" option enabled _and_ defining the PAC detail in the VPN Tunneling connection profile ... View more